A 1-year follow-up of a multi-center treatment trial of adults with anorexia nervosa
J. Yu1, W. Stewart Agras1, K.A. Halmi2, S. Crow3, J. Mitchell4, and S.W. Bryson1
1Department of Psychiatry, Stanford University School of Medicine, Stanford, CA, 2Department of Psychiatry, Weill Medical College of Cornell University, White Plains, NY, 3Department of Psychiatry, University of Minnesota, Minneapolis, MN, 4The Neuropsychiatric Research Institute and Department of Neuroscience, University of North Dakota, Fargo, ND, USA

Abstract

OBJECTIVE: To examine maintenance of recovery following treatment in an adult anorexia nervosa (AN) population. METHOD: One year follow-up of a randomized clinical trial with 122 participants treated with: cognitive behavioral therapy (CBT), drug therapy (fluoxetine), or a combination (CBT+fluoxetine) for 12 months. Participants were assessed at baseline, end of treatment, and follow-up. The primary outcomes were weight and the global scores from the Eating Disorder Examination (EDE) separately and combined. RESULTS: Fifty-two participants completed the follow-up. Mean weight increased from end of treatment to follow-up. Seventy-five percent (75%) of those weight recovered at end of treatment maintained this recovery at follow-up. Recovery of eating disorder psychopathology was stable from end of treatment to follow-up, with 40% of participants with a global EDE score within normal range. Using the most stringent criteria for recovery, only 21% of the completer sample was recovered. DISCUSSION: The findings suggest that while adults with AN improve with treatment and maintain these improvements during follow-up, the majority is not recovered. Additionally, further research is needed to understand barriers to treatment and assessment completion. (Eating Weight Disord. 16: e177-e181, 2011). ©2011, Editrice Kurtis

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